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Reversing Autism with The Nemechek Protocol – Update 2017

Reversing Autism with The Nemechek Protocol – Update 2017
March 20, 2017 Dr. Patrick Nemechek and Jean Nemechek

Nemechek Autonomic Medicine Autism 2017There is growing scientific evidence that an imbalance of intestinal bacteria called SIBO (Small Intestinal Bacterial Overgrowth) along with excessive inflammation within the brain are responsible for the features associated with Autism as well as ADD/ADHD, mood disorders, and developmental delay in children.

Bacterial overgrowth occurs when large numbers of bacterial that predominantly live in the colon migrate upwards, and increase the number of bacteria within the small intestine by 10,000 to 100,000-fold. This added bacterial load in the small intestine has two consequences that contribute to Autism.

First, the bacteria often tend to be of a clostridium species which can produce propionic acid in massive amounts. Propionic acid is a short chain fatty acid that is normally produced in small amounts within the intestine but the higher concentrations are being linked to some of the behavioral aspects of autism.

In animal studies, high propionic acid leads to the development of antisocial behaviors, increased sensitivity to sound, light, and touch, as well as gait abnormalities. In human studies, children with autism have very high concentrations of propionic acid within their tissues.

Secondly, the increased concentration of bacteria within the small intestine causes leakage of pieces of bacteria into the large concentration of immune cells that surround the small intestine and triggers the inflammatory reaction referred to as leaky gut.

A TESTIMONIAL

Hello! Just wanted to share that I started my Autistic/Apraxic 3 year old son on your protocol almost a month ago. He had about 10 words before this, averaging 1 new word a month prior. He has since, in that short time had an explosion of speech. He has been saying now about 1 new word a day, said 3 new words just yesterday, and has even spoken a few 3 word sentences. I felt hopeless before trying your protocol and cannot believe the large gains we are seeing so quickly! Thank you thank you thank you!!!!!!!   –   A Mom on Facebook

Leaky gut causes an increase in peripheral pro-inflammatory cytokine levels and allows for the inflammatory priming of a specialized form of white blood cell known as microglia within the central nervous system.

The combined production of inflammatory cytokines and activated microglia are primarily responsible for the developmental issues, seizures, sensory issues, mood and attention disorders commonly associated with autism.

A child is born with approximately 100 billion neurons and over the ensuing 18 years, needs to prune these neurons down to 50 billion in a process referred to a synaptic pruning. Excess inflammation from leaky gut, microglia priming and omega 3:6 imbalances prevents otherwise healthy microglia from pruning fast enough, and results in developmental delay.

The priming effect from the bacterial overgrowth causes many microglia to shift into the M1-phenotype, and results in the brain being less able to fully repair itself from commonplace physical (falls and bumps to the head), emotional (fear, abuse, neglect) and inflammatory (surgery, infections, vaccines) brain injuries.

A small residual amount of damage will remain after each injury, and each new injury leaves residual damage upon the prior injury in a process referred to as cumulative brain injury. The abnormal neurological functioning from cumulative brain injury can occur slowly over time and or rapidly depending on the intensity of the brain injury. Damage to different portions of the brain will result in different outward symptoms such as ADHD, chronic anxiety or gait abnormalities.

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The elevated inflammatory cytokines are also able to turn on certain genes that are linked with autism and may be responsible for certain features or more severe forms of Autism.

And finally, the excessive inflammatory environment in the brain reduces the seizure threshold and make seizures more likely to occur. The drop in the seizure threshold from inflammation is seen when young children without Autism develop febrile seizures with the fever and inflammatory reaction that occurs with simple upper respiratory viral infections or middle ear infections.

My understanding of the bacterial and inflammatory features in Autism have opened the door for me to provide groundbreaking treatment. The bacterial overgrowth increases propionic acid levels that cause kid’s brains to function differently, almost like a chemical impairment or slight intoxication, and at the same time the inflammation prevents normal neuron pruning and development as well as inhibits normal brain injury repair.

My approach to reverse the key components in Autism is straightforward. To provide the brain with a healthy, non-inflammatory environment to function more normally and to allow microglia to correctly prune and repair the brain, we need to reverse bacterial overgrowth and suppress the production of inflammation cytokines that are produced from a variety of sources.

By applying a logical understanding of science, I have focused application of The Nemechek Protocol™ medical consultation and treatment services on Autism, and have reversed the key features of Autism in many children.

The Nemechek Protocol for Autism uses a prebiotic fiber called inulin to reverse and control bacterial overgrowth, and high doses of omega-3 fatty acids to normalize microglial function and normalize the inflammatory state within the brain.

Cooking with domestic extra virgin olive oil also helps reduce brain inflammation resulting from linoleic acid, an omega-6 fatty acid found in in high concentration in cooking oils and processed foods.  Inulin is a natural fiber found in onions, garlic, artichokes, agave, chicory root and many other plants.

When buying powdered inulin, I avoid ones that also contain probiotics or digestive enzymes as these ingredients can makes some aspects of Autism worse.  (See my post on probiotics for more info on this topic.)

I find that 2-4 inulin gummies or 1/2 to 1 teaspoon of powdered inulin daily can reverse bacterial overgrowth enough to allow an autistic child (2-8 years of age) to become much more aware and interactive with their environment within a few weeks. And depending on the amount of underlying developmental delay, children will often start speaking within a few weeks to a few months.

Remember this is a simple plant fiber found in foods we eat every day, and is safe in children. If children get a little gassy or bloated, I recommend cutting back on the dose. Inulin is heat-tolerant and can be mixed or sprinkled over any form of liquid or food.

To help reduce the inflammation within the brain and normalize the behavior of microglia, my autistic patients are placed on omega-3 fatty acids (EPA and DHA) from fish. A recommended starting dose for small childrens is about 600 mg of omega-3 (the total of EPA plus DHA) per day.  DHA is particularly important as it is the main omega-3 in the brain.  (Read this post for more information on DHA as brain food.) Omega-3 fatty acids may be given in the forms of simple fish oil mixed in their food or drinks.

I don’t recommend fermented fish oil.  And when dosing I tend to increase the dose of omega-3 is the children are older (specific dose for varying ages of children can be found in The Nemechek Protocol for Autism and Developmental Disorders)  When in doubt, I favor a high dose.

If children have difficulty with diarrhea or prior problems with fish oil causing diarrhea, I have the kids start inulin fiber alone for 2-3 weeks in order to let the gut bacteria balance out, and then slowly increase the dose of fish oil and usually the tolerance is much better.

Whether the parents use Nordic Fishies or or another brand of liquid fish oil, I recommend they buy a high-quality brand as there is a very high level of fraud in the supplement industry.

All families are asked to cook their foods in domestic extra virgin olive oil (EVOO).  EVOO contains 70% oleic acid, and oleic acid reverses the underlying inflammation coming from excessive linoleic acid toxicity.  (Watch my screencast for more information on the benefit of olive oil.)

Linoleic acid is most commonly found in the unnatural vegetable oils added to the foods we purchased.  (See my other post about omega-3/omega-6 rebalancing for more information on this topic.)

The bigger, older children with autism require more effort and higher doses of inulin.  To gain better control of SIBO in older children I often treat with a 10-day course of Rifaximin (Xifaxan in U.S.).  Rifaximin is a non-absorbable antibiotic that is only used for other bacterial overgrowth conditions (hepatic encephalopathy and IBS with diarrhea).

Follow-up use of inulin after Rifaximin is sometimes used if intestinal symptoms are still present.  If inulin does not make any significant difference as a follow-up therapy, I stop it.  I never add probiotics after resetting with Rifaximin because probiotics can easily make things worse even if they helped prior to the use of Rifaximin.

The reversal of bacterial overgrowth with inulin results in a drop of propionic acid and can result in a sudden improvement in function within a few weeks.  But many children do not fully return to normal because they still have underlying developmental delay (some quite severe) as well as ADD, ADHD, sensory issues, seizures, as well as chronic depression, anxiety or aggressive behaviors. ( Watch my screencast about how leakage of LPS from bacterial overgrowth prevents the brain from fully recovering from injuries.)

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These remaining conditions take longer but week by week things can slowly improve.  If there is no significant improvement within 2 months, I generally increase the dosage of omega-3 fatty acids. If things still do not improve or seem to plateau after a couple months, I now add bioelectric Vagus Nerve stimulation to the Nemechek Protocol with good results.  (See my screencast about vagus nerve stimulation.)

The brains of older kids that have experienced prolonged bacterial overgrowth and inflammation as well as more brain injuries that occur over time, generally take longer to show improvement but I have seen significant progress in older kids as well.

I care for 2 teenage non-verbal autistic boys (14 and 16 years of age), and although they showed signs of continual improvement, they took about 4-5 months to begin speaking.

More recent is a remarkable case of a 23-year-old non-verbal autistic girl with frequent seizures. Within 8 months her seizures had reduced from 5-7 per day to 2-3 per week, and she can now write her name and converse in both Spanish and English (she lives in a dual language family).

For autistic children, the Nemechek Protocol will need to be daily and possibly forever but the benefits are life changing. Inulin fiber, omega-3 fatty acids and olive oil are from natural sources, are commonly consumed by most of us every day, and are available without prescription.

I am a classically trained internal medicine physician (D.O.) from UCLA and my Internal Medicine and Autonomic practice is in the Phoenix area. My research background has been focused on the Autonomic Nervous System, brain metabolism, and metabolic inflammation.

I use all available scientific and medical tools to induce the nervous system and organs to repair themselves by normalizing inflammation control mechanisms, inducing natural stem cell production, and re-activating innate restorative mechanisms.

March 23, 2017 –  An Addendum on Recovery

My Experience with Autism Recovery:

Uniformly all the kids under my care (50-60 to date) seem to be improving in significant ways.

In terms of speech, some younger kids start speaking within a few weeks while kids in the teens might take 4-6 months.  Our 23-year-old patient didn’t start speaking until after 8-9 months of treatment.

Importantly, even the most severe cases have a noticeable improvement in their awareness of their surroundings within a week or 2.  I interpret this as a decline in the toxic effect of the propionic acids on their brains.  Parents report more eye contact, awareness or acknowledgement others have entered the room.  They also seem more tolerant of being touched or held, or are more willing to approach someone and be physically close to them.

After the first few weeks, recovery rates are highly variable, and I believe this is due to the degree of developmental delay underlying the toxic state.  If the inflammatory cytokine process has been going on since birth, there can be so much developmental delay as to be labeled mentally retarded.  But if the developmental delay is simply mild, kids may seem very functional quickly.

The important point to remember is that your child’s brain and an enormous capacity to continue the path of development once the inflammation is controlled.  Neuronal/synaptic pruning will re-initiate, and according to the developmental delay literature, they can catch-up about 2-3 months of development for every 1 calendar month.  In my estimation, it seems to advance this fast if not faster.

The underlying wild card is what gene has been activated by the inflammation and what might it do to the neurological impairment of your child’s brain.  The inflammatory environment that prevents normal synaptic pruning and recovery from brain injury also triggers the litany of genes being found in autism.

Inflammatory cytokines abnormally produced by the mother are affecting the child’s nervous system within the womb, and then the imbalance of intestinal bacteria of the child as well as high omega-6 food sources continue to fuel the inflammatory process within the child after birth.

These inflammatory cytokines are the primary process through which the genes within the DNA that had been dormant for 1,000’s of years in the child’s ancestors are finally activated, begin altering how cells function, and contribute to the overall variety of neurological, behavioral characteristics that manifest in autism.

Here’s the potential for recovery in the autistic brain. A 23-year old non-verbal autistic female (Lennox-Gastaut Syndrome), was having 6-8 seizures per day and had never held her parents gaze for her entire life.  She did not like to be held, could not color or write, and sat curled up in a chair most of the day rocking.

Within 2 months’ of starting our protocol (rifaximin, high dose omega-3 fatty acids, and mother cooking with California olive oil), her seizures had dropped to 1-2 a day, she would sit upright in a chair and she slept through the night.

At month 4 she started looking her parents in the eyes and holding their gaze, and was more able to be touched and hugged.

At her month 6 office visit, she started smile at me, her seizures had reduced to 1-2 per week, she could now write her name (although she had never been shown previously) and could draw objects that were recognizable.

At 8 months, she began speaking rudimentary Spanish and English (dual language household) but emotionally is behaving as if she is 3 years old.

At 18 months, she speaks very clearly in full sentences, her seizures have declined to 1-2 per month (despite discontinuation of 2 seizure medications), and her emotional maturity has risen to about that of a 4-5-year-old.

But don’t despair. No matter how badly the developmental delay has slowed brain maturation, the potential for an unbelievable recovery is present.  We are beginning to understand that once human genes are turned on by inflammation, they can ultimately be shut back off again once the inflammatory environment within the body is significantly reduced.

Do your best to be patient and give this approach a chance.  Because the path to recovery over all things medical is 3 steps forward, and 1-2 back, compare today’s behavior to last month’s, not yesterday’s. The neurons within the human brain, like your hair, can only grow and change only so fast.

Every month, your child’s brain has the ability to “catch-up” 2-3 months in development.  That means every calendar year, they may catch-up 2-3 years.  I believe once the inflammation is suppressed, all that is required for recovery is a good solid inflammation suppressing regimen and patience.

May 26, 2017 – Addendum on The Misconception of Feeding Bad Bacteria and Yeast

The conclusion that increased stemming, less sleeping or increased anxiety is from inulin feeding “bad” bacteria such as Klebsiella has been a concern of several commenters.

I’m not saying this is impossible but I do not believe that to be the case, and have never seen such a reaction in the many children I’ve worked with. There are several reasons for this.

First, inulin’s main effect is within the lumen of the small intestine where bacteria digest inulin through a process referred to as fermentation. The primary effect is the production of the healthy short chain fatty acid known as butyric acid. Only small amounts pass through to the colon.

Secondly, a significant increase in pathogenic bacteria, or overgrowth bacteria would almost certainly cause an increase in diarrhea, stool frequency, abdominal cramping, reflux and eczema. We do not see this, and in fact there in general a reversal of these symptoms with the use of symptoms with the use of inulin.  If the intestinal ( not neurological or behavioral) symptoms were to worsen on inulin, I would suggest the inulin be discontinued and would suggest using Rifaximin.

The development of constipation with the use of inulin is a sign of underlying autonomic dysfunction from developmental and cumulative injury that eventually reverse after a few months of fish oil.

Thirdly, propionic acid has a sedating effect on children, almost as if the children had been taking Valium or Xanax. Therefore, once inulin reverses the bacterial overgrowth and the propionic acid levels decline, the children will come out of their stupor. There behavior at this point is predicated but their pre-existing developmental abnormalities and cumulative brain injuries and not some toxic effect of inulin.

A fourth point is that the detection of pathogenic bacteria such as Klebsiella in the stool by no means suggests these bacteria are present within the small intestine where inulin has it’s main effect. Detection of pathogenic bacteria such as <em>Klebsiella pneuomiae</em> or <em>Clostridium difficle</em> are commonly in asymptomatic patients and are essentially harmless. Their growth is kept in check by a healthy balance of other bacteria which is further bolstered with inulin.

Buy Your Copy of The Nemechek Protocol for Autism and Developmental Disorders Today!

And finally, some parents are worried about overgrowth of candida. I agree that candida and other yeasts/fungi inhabit the intestinal tract but more detailed studies demonstrate yeast/fungal overgrowth does not occur in autism. And while the observations of clinical improvement about reduction of sugars and etc. are correct (think GF/CF, FODMAPS, GAPS), they were misattributed to yeast instead of the bacterial overgrowth for which we have mounting evidence.

Because of this, I believe the use of potent anti-fungal drugs is unwarranted in the specific treatment of autism.

Hope this helps.

© 2017. Dr. Patrick M. Nemechek and Jean R. Nemechek. All Rights Reserved. Patent Pending.

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Dr. Nemechek
Dr. Nemechek

Please use the search feature on this blog to find answers to your questions. Many of the questions that are being asked have been answered repeated by me (Dr. N) in the past.

Thank you.

Swathi
Swathi

Hi Dr, My son is almost 4 yr old ,on protocol since 9 months He is having gains in speech like repeating words which became more and more daily,now a days she sings rhymes few times on his own.But eye contact , awareness and hyperactive not improved,we had a Skype session with you in September you have asked to increase inulin 1 tsp Now he is on 1 tsp inulin since almost a month ,1ml FO and Evoo cooking . He is sick since a month like on and off cold and cough ,fever Should I increase the dose of… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The increase in speech tells you he is recovering and the remainder is just taking longer to recover.

There is no need to alter doses during common infectious events.

Claudia
Claudia

Hi,

My son was diagnosed with Hypomyelinating Leukodistrophy type 6. Could your protocol help improve myelination in this case?

Thanks a lot!

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’m uncertain but the protocol is very effective at reducing excessive inflammatory stress throughout the body and it is highly probable that excessive inflammatory stress that is most likely active in your child’s body is interfering with myelination.

Double check with your physician to be certain the fish oil and olive oil would not interfere with another treatments your child might be receiving.

Sadaf
Sadaf

Hi DR greetings! I’m here to get a help from you again… my 7 years son is into your amazing protocol last 11 months,,, he is suffering from tonsills and after being observed with drs since last 5 months back we all decided for adenotonsillectomy which is commonly done for either chronic adenotonsillitis or for chronic hypertrophy of tonsils as said by dr,,,, my question is the operation date is 1 of jan should I continue protocol before n after the operation or gave a gap for a month as omega is blood thinner is it safe for my son…… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I would continue the protocol throughout the process.

Fish oil is not a blood thinner (does not decrease the ability of healthy persons to form normal blood clots) but rather prevents the formation of excessive, abnormal clots (think deep venous thrombosis, stroke) from occurring due to its anti-inflammatory action. The 2 effects sound similar but are quite discrete.

Since you are concern I recommend asking the surgeon and following their advise.

Cesar
Cesar

Dr. Do you think than brócoli seeds help or potent the protocol? Do you recommender ir?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

No I do not recommend this to my patients.

Masa
Masa

hello dr Nemechek,
I know you are saying no to probiotics. As Ive been reading you are allways talking about probiotics containing large spectrum of live cultures. But what about adding probiotics containing only one culture like lactobacillus reuteri? Im asking cause there are researches about L. reauteri reversing ASD like:
https://medicalxpress.com/news/2018-12-microbial-based-treatment-reverses-autism-spectrum.html
Thank you.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Of course everyone if free to make their own decisions on this matter but I still very strongly recommend using any probiotic regardless of how na=many strains it contains.

Ria
Ria

Hello Dr. i have read your book and about to start the protocol with my son 2 yrs old diagnosed with GDD due brain damage, physically he is still at a 6month old level. will the protocol help with physical and motor skills? pysiotherapy seems to be helping very minimally. Cognitively and socially he is behind to but seems to be doing better and catching up. Thanks for your time and keep up the wonderful work you are doing for our kids. God bless you

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Yes, this protocol often helps fine and gross motor skills in addition to the other developmental issues.

Edward Amos
Edward Amos

good post

Anonymous
Anonymous

Hello doctor my son 5 year old 9months on protocal he is having fever from past 5 days 102 ; 103 high fever dotor said upper respiratory infecton but he is saying itxhing on his palms and legs we r at 2 tspoon of inulin is this itching because of bacteria dieoff from inulin which his liver is not able to detox im woried he is having high fever from5 days do u think i should stop inuin on fwver and see if itching goes

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The itching is more than likely from the infectious agent causing the fever.

Winnie Wong
Winnie Wong

Hi Dr. Nemechek

One of my boy has mild ADHD and I’m starting him on this protocol (start on Inulin and stop probiotics and Omega-6). However, my another two kids are not but based on your book, it appears to me that this seems inbuilt into everyone. Today they are taking Biolife Prebiotics and Probiotics and Nordic Omega Junior with Omega-3-6-9. As such, should I also put them strictly into no probiotics and Omega 6 as well?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Yes

jamuna
jamuna

Dear Dr Nemechek thanks for your quick response on yesterday. we gave our fiver year old kid 8g inulin per day . actually we use teaspoon to Gramm conversion software tool , and it indicate one teaspoon equal to 5 Gramm , so we decided to give him 8 Gramm per day, we didn’t control NOW inulin bottle label for measurement , there now we found one teaspoon os equal to 2.8gramm inulin. we did missed conversion and gave him overdose , now we fear about last 5 month overdose, doctor is overdose inulin cause any issue or side effect?… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’m sorry but due to the high volume of requests, I’m restricting my response to those involving a broader level of explanation and am refraining from providing individual dosage advice.

I believe the answer to your questions can be found in our protocol. A copy can be purchased at https://autonomicrecovery.shop.

Winnie Wong
Winnie Wong

Hi Dr. Nemecheck My son is 7 and has mild ADHD. He is not under any medication but we are giving him Nordic Omega Junior 3-6-9, biolife prebiotics and probiotics and magnesium. I just goto know about the Nemecheck protocol. I understand I have to put him on inulin (prebiotics only and no probiotics) and omega 3 only. Hence, I’m thinking of buying him the nordic omega-3 liquid purified and inulin powder but but not sure how much dosage and the duration. Separately, back here in Malaysia, I’m not sure how I can get more consultation of this protocol so… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’m sorry but due to the high volume of requests, I’m restricting my response to those involving a broader level of explanation and am refraining from providing individual dosage advice.

I believe the answer to your questions can be found in our protocol. A copy can be purchased at https://autonomicrecovery.shop.

Kari
Kari

I have read that you recommend stopping all other supplements before starting the protocol. My son is 8 and ADHD. He takes magnesium, B6, iron, D, melatonin and CBD oil. Would this include stopping the CBD oil? And the melatonin? (We are in Canada and have a medical prescription for the CBD oil from a pediatrician).

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I stand by my recommendations and I have never required CBD in order to help a child recover.

Baskar
Baskar

Dear dr nemechek

Our 5.5 years old boy on your protocol withiout any supplements, he is on now inluinn 8g , NN pro omega 3 1000mg and 7.5 ml California EVOO .he have major improvement, but still non Verbal , Now our pediatrician check his vitamin d , iron , he have vitamin d3 16ng/ml , and she gave vitamin d3 supplements. I have questions, do you recommend vitamin d3 supplements, or Nordic natural cod liver oil along Nordic natural proomega 3 .

Thanking you

Faithfully
Jamuna

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I prefer vitamin and minerals to come from food over some abstract pill. I would consider CLO an acceptable source of vitamin D.

Unless it’s a miscalculation, your inulin dose is very high.

Jules
Jules

“There is growing scientific evidence that an imbalance of intestinal bacteria called SIBO (Small Intestinal Bacterial Overgrowth) along with excessive inflammation within the brain are responsible for the features associated with Autism as well as ADD/ADHD, mood disorders, and developmental delay in children.”

This looks like a promising avenue of research for me to understand this thing that has my child. Please could you post some links to the papers, so I can understand and show others?

Thank you

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

There is a wide variety of references in the back of our protocol.

A copy can be purchased at https://autonomicrecovery.shop

Hannah
Hannah

Hi Dr.Nemechek, My son is on his 16th month on the protocol. And for the last 5 days his fever wouldn’t go away. It’s on and off from 37.7,38.5,39.3 all in celsius. Last 2 days ago we sent him to GP and he has prescribed Augmentin to my 5 yr old son.Yesterday we skipped giving him the protocol because we noticed everytime we would give it or the Augmentin his fever would spike up high again. Any advice?The GP told us to send him to Emergency if after 3 days of Augmentin his fever is still not going away. I… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

If there is an interaction between the antibiotics and your child being on the protocol, stop the protocol for the while you finish the antibiotics then restart.

The inflammatory stress of the infection itself can cause a mild relapse but he will recover from this as he would any other mild head injury that child experience.

Keep up the great work.

baskaran
baskaran

Dear Dr Nemechek

our 5.5 years kid on your protocol without any supplement around one year. he have some major improvement but still he is non verbal. we gave hime 8g NOW inulin, 1000mg NN pro omega 3 , and 7.5 ml California EVOO. now last two week I have urinary tract infection first time in his life. , but our pediatrician not gave any antibiotics still now. doctor what you suggest us, could we need to decrease or increase inulin Dose?

Thanking you

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I do not believe the inulin can cause his bladder infection.

If your child has one, he might need antibiotics. Either there is confusion with what your doctor told you or maybe you should seek a second opinion especially if your child is acting ill.

Fil Anna
Fil Anna

Hello dear Dr. N!
I’m really worried about new destination series of evoo.
I live in Ukraine and order everything from the USA.
Now I’m afraid this new series will be fraudulent too… Because it will no longer have cooc certification.
Could you please share your opinion on this topic?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I was just made aware of this 2 days ago and am working on some guidance for everyone.

I’ll post it within 1-2 days

Jyoti
Jyoti

Sir, I am having a question regarding inulin and fish oil.
Can both of them be given together in a single meal. Eg. Can I mix both inulin and fish oil in porridge and feed to my 3.5 year old kid.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Yes, they can be mixed without any harm to the child or their effectiveness.

Frosina
Frosina

We started the Nemecheck protocol for our 5 year old son on Octomber 13th, 2018. today we finaly made EEG for first time and we find out that he has idiopathic epilepsy, but we never had seizures, we never notise tham, our doctor insist we to go on with this protokol, but she recomends GAMIBETAL (GAMMA AMINO BLITRIC ACID), so mu question is : Is it save to give gamibetal whit this protokol?
Thank you

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I have no experience with this supplement but I generally recommend following the advice of your physician since they are aware of the particular issues surrounding your child’s health

Joel
Joel

Hello Dr Nemechek. My son has been on the protocol since 11 months and every time I increase his inulin dose by 1/8 I see increase in awareness which goes away in a few days. He is getting 2.5 teaspoons inulin,2.5 ml ultimate omega and 1 Tablespoon evoo.he is 5 . Should I consider rifaximin ? Or continue giving him inulin.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The major question s whether or not you continue to see substantial improvement overall during the 11 months.

I’m sorry but due to the high volume of requests, I’m restricting my response to those involving a broader level of explanation and am refraining from providing individual dosage advice.

I believe the answer to your questions can be found in our protocol. A copy can be purchased at https://autonomicrecovery.shop.

Anonymous
Anonymous

Hi Dr. Nemechek… I just found out we are expecting baby #2 and I would like to prevent the same outcome I had with the first as much as possible..
I am curious how much Fish oil I should be taking. In the book it says expecting mothers should consume 2,000-3,000 mg fish oil a day, but is that DHA and EPA combined ? Or just DHA alone??
Thank you!!!

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Combined and and I recommend the typical EPA>>DHA blend during pregnancy

Mridula kundu
Mridula kundu

Hello Dr.Nemchek
I am Mridula roy from Belgium.
My daughter is 6,Non verbal Asd.studying your research and blogs,I feel that its vaccine what caused SIBO in her case.she had lot of vaccine(non mandatory also)and now from school,she needs DPT and polio booster.as per Belgiun rule,its should be done within 6-7yr age. How much it will effect her development with NP?
She is 8 months on NP.she had some behavioural gains but no speech and socail communication developed.
Her dose now
Inulin 1.5tsp+ 1/8tsp(since 2 days)
NN ultimate omega 2ml
California EVOO 1 tbsp+cooking
Thank you for your time.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I discuss the impact of vaccines in our protocol. A copy can be found at https://autonomicrecovery.shop.

Mridula kundu
Mridula kundu

Thank you Dr.Nemechek for your kind reply.
I will definitely reread the book.

baskaran
baskaran

Dear Doctor thanks for your great solution to autistic kids. our 5.8 years old boy on your protocol without any supplement, now we gave him 8g NOW inulin , 1000mg NN pro omega 3 , and 1 Tbsp California EVOO, almost one year he is on your protocol , and he have some major improvements, but still non verbal. last time we measured vitamin d and ferritin and the values are 17ng/ml , and 49 microgramm/l . he is on protocol almost one year but still he didn’t speak any words. please give us suggestion. we keep him Casein free… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’m sorry but due to the high volume of requests, I’m restricting my response to those involving a broader level of explanation and am refraining from providing individual dosage advice.

I believe the answer to your questions can be found in our protocol. A copy can be purchased at https://autonomicrecovery.shop.

Sadaf
Sadaf

Hello’ my son is 7y old he has epilepsy when he was 4 y 8m old he got two episodes continues 30min long with 3 months gap each he is now on medication and got no seizures last two years but I started protocol last week and tomorrow he got a sezuire for 1 min long he had focal epilepsy wht to do now stop the protocol i m so confused please anyone help me or guide me please

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I know of no evidence that fish oil, olive oil or inulin (the fiber in onions or garlic) would trigger seizures.

Consult you managing physician and it they approve, continue with the protocol.

Many other things such as mild viral infections, emotional or physical trauma might trigger a brief seizure if indeed that is what you witnessed.

Parent
Parent

Dear Dr Nemechek,

We have started the protocol for our 7yr nonverbal autistic son.His eye contact has improved.Below is his dosage,Pls review and advise:
5ml ultimate Omega 3(NN)
15ml EVOO dolce Vita brand from Italy.
Cooking with cold pressed coconut oil.
0.5 tsp NOW inulin.

Do we need to change anything in the protocol to see faster gains?

Thanks in advance,

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’m sorry but due to the high volume of requests, I’m restricting my response to those involving a broader level of explanation and am refraining from providing individual dosage advice.

I believe the answer to your questions can be found in our protocol. A copy can be purchased at https://autonomicrecovery.shop.

Noelle
Noelle

My kid is having bad cough,fever and flu. She has been on your protocol for about 5weeks. I had given her medicine( prospan &kaloba syrup & paracetamol . Will these medicine cause relapse?thanks

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Those medicines shouldn’t but the inflammatory stress from the flu might.

But as long as they were showing some recovery prior to the flu, the same protocol dosages will help them recover with increasing doses.

Noelle
Noelle

Hi Dr. Nemechek, Is it okay to carry on TCM acupuncture (no herbs/herbal medicine involved)while doing your protocol? (the practitioner will usually use alcohol swabs and disposable needles to perform accupunture)
Thanks for your advice.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I don’t see any problem with acupuncture in conjunction with my protocol.

Anonymous
Anonymous

Hello doctor WE r 8 months on protocal my 5 yr old started climbing furniture kitchen countertops im giving 2 tspoon of inulin from past 3 werks havent seen gains yet he is very hyper stimming climbing no gains he used to do this climbing long back and he stopped now he started doing i read climbing and gigling is yeasty behaviours we r worried that inulin is really feeding yeast now do u think climbing is related to yeat behaviours thanku

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

These are not “yeasty behaviors” and inulin does not feed yeast.

Something else has occurred if this just started in the last weeks but you have been on the protocol for 8 months.

If you just raised the inulin dose, these are more awakening symptoms. Simply back off the inulin dose some.

Billie
Billie

Dear Dr Nemechek, Fist of all, thanks for all the videos that you made. No questions, just update. My twins 6 yo are doing well on the protocol. We started protocol at the end of September 2017, but we didn’t have the NN fish oil until January 2018, and with got rancid bottle 🙁 which set us back. Twin A, had ASD, barely verbal, few words: twin B, other developmental delays ADHD.. etc.verbal, but could not form sentences. We did have awakening period immediately. Hyperactivity increased, twin with ASD, started bed wetting at night, that resolved after week or two.… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I agree, focus on the therapies that are more comfortable with them. We have seen many kids who demonstrate some sort of relapse associated with the stress of ABA, a different therapist, or a new school.

I’m confident their ability to handle the stress with improve as well.

Anonymous
Anonymous

Hi Dr,
I am from Australia. I went to purchase rifaximin and was shocked to hear its in the $500 dollar mark.
Any idea how Aussies are getting this prescription?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’m not exactly certain about the regulations in Australia but many in the U.S. are purchasing it from online pharmacies.

Zebo Narimanova
Zebo Narimanova

Hi Dr Nemechek, We started your protocol for our son 4 months ago. He is 3 years old now. He is taking 1/2 teaspoon of inulin, 2ml of NN fish oil and olive oil in food. We noticed immideate improvements then in my son. He started sleeping through the night which he never did before. Also, he developed very good eye contact, good motor skills and strated to follow my instructions. However, for the last 3 weeks , he has been reversing back to the point where he was before. More meltdowns, lack of eye contact and waking up at… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Something must of changed in the last 3 weeks – foods, supplements an intestinal virus. Only option might be to bump up the inulin to 1 tsp per day.

Rachael
Rachael

My 3 year old Autistic daughter turns 4 in January we started the protocol on 17th August 2018. Her doses are 1/2 tsb inulin twice daily, 5-10mls EVOO daily, and EPA 500 (3/4 of a capsule) . Previous to starting the protocol had 200 single words not used everyday day and did not and still does not initiate conversation however in the last couple of weeks had started copying short phrases from her favourite Television shows. My questions is, will conversational language develop from here. Will she start to ask questions as time goes bye?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Yes, her speech should continue to improve in complexity

Hilda Sancen
Hilda Sancen

Hello Dr. Nemecheck! My grandson have been 15 months in the protocol, He’s almost 5 years old, 6 weeks ago he started stuttering and seems to be getting worse o evolving like his speech therapist said, he started repeating a few words, now he’s having trouble starting the words, doses are 1000mg omega 3, 1/2 tsp inulin, cooking with EVOO, all recommended brands, he’s not been physically sick, but he was under so much stress due to changing his ABA technician 4 o 5 times in two months, I didn’t change the doses in the last 8 months ( maybe… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I would interpret the new symptoms are coming from an injury – possible an emotional trauma from the new therapist or even the ABA itself.

Sally
Sally

My 4 year old is on the protocol. Is it ok to get a flu jab (spray in nose) while on the protocol?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I discuss my concerns about vaccination in the book but beyond that you’ll need to make the decision in conjunction with your pediatrician

Vijay
Vijay

Why do you think homeopathy will interfere with NP . Homeopathy usually works restoring the nature balance of the body just like NP. And I feel it will support each other.
Thanks for your response

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Regardless of the intent or natural origin, I have found a wide variety of other supplements, herbals, etc will prevent recovery and at times even cause them to dramatically lose recent gains. I don’t know why but my focus in singular, get the children to recover from the underlying developmental issues and cumulative brain injury that is present.

Gupta
Gupta

Hello Dr, My son who is 7 yr old is on protocol from last 5 months and saw very little gain and waiting to see more in coming days and months. Current dosage is 1 and 1/2 tsp Inulin, 3 ml Ultimate Omega 3 (NN) and EVOO 20 ml. My son’s neurologist prescribed MRI Scanning of brain for which my son has to get anesthesia. So my question is after anesthesia should i keep my son on same dosage or give couple of days gap and start again with low dosage. For my son when we started him on protocol… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Continue the doses through the testing without any interruption

Arjun
Arjun

Hello Sir,
My son is 2.3 years old, he is having ASD symptoms, from last 2 month we are giving him Homoeopathic medicine,
Now we are planning to start the Nemcheck protocol, can we continue giving him homoeopathic medicine along with Nemcheck protocol.
Regards
Arjun

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I don’t recommend combining the 2 approaches.

Charvi
Charvi

Hello Doctor,

Reading your book gives us so much of knowledge and hope.
God bless you for your magical research and providing such a simple yet effective protocol for better quality of living.
What are your thoughts on lecithin in plants ? Are they not harmful. There is lot of research into this concept of developing a lecithin blocker to protect our body and gut from lecithin. Please confirm if lecithin in food is safe or harmful. If yes , how does The protocol help.

Thanks

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I think lecithin is harmless.

RoseAnne Stanton
RoseAnne Stanton

Hi, Is weight gain normal on the protocol? My stomach is also larger and on the harder side. Just bloating?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Weight gain is not common.

Anonymous
Anonymous

Can you explain more about the “overgrowth reaction” you just mentioned? I saw above that you said “an overgrowth reaction to the fish oil (as one can with tomatoes, orange juice or bananas for instance)” Since we are not on any special diet I was unaware of which foods can cause an overgrowth reaction. Can you explain what about fish oil, tomatoes, oj and bananas contributes to the overgrowth? Is it the sugar?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Its just that if you have overgrowth in the small intestine, the foods seem to make you feel ill in some way. Its not really the fault of the foods, its due to the abnormal amounts and types of bacteria within the small intestine.

Watch my video on “There is No Such Thing as Inflammatory Food”.

Anonymous
Anonymous

Hi Dr. Nemechek,

Do you know if the Nemechek Protocol could offer any benefits or healing for children with NGLY1 Deficiency? If so, could you offer any guidance about how it might help?

Thank you!

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I am unaware of any child with NGLY1 Deficiency being treated with my protocol but it has helped a variety of other children with a variety of genetic issues.

As long as your managing physician gives there approval, its worth a try.

Paul
Paul

My son is 22 years old and has ASD. He has been on the inulin nad DHA since August nad has always only had virigin olive oil. We have seen some improvement.
My question is about tVNS. At what stage should we conmsider usingig it and what sort of methos do you suggest (how many hours per day and what sort of current level).
Many thanks

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The VNS is added as adjunctive therapy only if there is a plateau in recovery.

VNS is done incorrectly can be dangerous and as such is limited as a Class II device and not available without a visit to a physician.

Paul
Paul

We are conducting tVNS under te supervision of a local Department of Psychiatry. They are suggesting 4 hours per day of tVNS which seems impractical for our son. Interested in your experience and if that amount of time is needed to have an effect. Many thanks

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The electrical characteristics and the time and pattern of delivery of the current during VNS all can vary depending on what clinical effect one is trying to achieve.

Oleh
Oleh

Hi. I am a doctor from Ukraine. Several months ago I bought your book. I have a question about candida. I knew your opinion about yeasts. So I made my little research and find some scientifical articles stated that autistic children have more than double yeast comparing to neurotypical. And that propionic acid is not the only metabolite that influences the brain. So my question is: does it mean that from your experience, using inulin supports so fast growth of beneficial flora that we can omit the candida issue? Very appreciate your answer. Thank you. PS. If you need I… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

There is no evidence of fungal overgrowth as a source of translocation, inflammatory cytokine production and production of propionic acid.

Inulin results in a increased acidification and increase in beneficial flora within the small intestine.

Valina
Valina

Hi Dr,
As what is mentioned as SIBO ( Small Intestinal Bacterial Overgrowth), is there anything called SIFO ( Small Intestinal Fungal Overgrowth).
They discussed this in the Integrative SIBO Conference 2017 at Lombard, IIlinois.
I agree with you that inulin doesnt feed fungal . But do inulin handle fungal overgrowth in small intestinal as well? Or is it that as bacterial overgrowth resolves, fungal overgrowth resolves as well. Sorry doctor, just trying to understand the concept overall.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

I’ve never seen any scientific evidence supporting the concept SIFO.

Leyla
Leyla

Hi dr nemecheck, I just finished the two weeks of the antibiotic along with all the oils all recommended brands. I know it will take sometime to see a difference but i have had sibo for 15 plus years im sure i have yet to feel different where my stomach is concerned instill have the same feeling of hot air baloon filling my stomach. Do you think i need to take another round ? I was hoping to plan for baby in jan/feb sometime. Does one who has had this issue for many years needs a longer treatmeat of the… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The bloating you are feeling is more from autonomic dysfunction than SIBO.

Continue the protocol and be patient.

Ram
Ram

Hello Doctor, Here is my original post about 11 months back and your reply – Very encouraging. Hello Doctor, We have some very interesting observations that makes me believe that the protocol is working for my son. We started the protocol from middle of June 2017 with Indian Cod Liver Oil, EVOO and NOW Inulin. From November, we give him 1 tsp of NOW Inulin, 6 capsules of NOW DHA500 and 1 tbsp of California EVOO. He just turned 18 in December. He is in Autism spectrum (high functioning – may be Aspergers). He has constipation problem too. 1. End… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Wow, you’ve really had some impressive gains.

I generally don’t repeat the Rifaximin unless there is clear evidence the intestinal symptoms that originally went away returned (See my YouTube on Sibo Fingerprint).

Many adults spontaneously relapse around 18-24 months so I will often repeat the rifaximin then.

Krys H
Krys H

8 months on protocol for my 3 year old non verbal ASD son. A month ago he became violent and aggressive towards himself and others. Should I remove inulin and do the modified protocol with just oils?

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

You could try but I think the issue is that a month ago he sustained some sort of injury that set him back.

Anonymous
Anonymous

Hi Dr, My son has been on the protocol for 15 months now. He is 11. He gets 1 tsp of inulin and we have him on the highest recommended dose of omega 3. He gets about a tablespoon of CA EVOO spread throughout the day and also cooked in foods. At this point do we just keep going and hope for recovery? We have been happy to have reduced some negative behaviors and he is more “with it” as they say. But he is no where near a typically developing child. My husband wants to take him to doctors… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

The only additional element that might help with his recovery is the addition of vagus nerve stimulation which would require a visit in my office.

Davinder Singh
Davinder Singh

Hi Dr Nemechek, My son is 4 years old and has been on the Nemechek Protocol for 10 month now. His dosage currently is half teaspoon chicory inulin, 1 NOW DHA capsule and half tablespoon California Ranch EVOO. We have seen gains with him but have stopped the inulin dosage at half teaspoon due to excess gas occurrence. We would like to book a personal consultation with you. Could you please advise if we should book a SKYPE session with you first or come out to see you? Many thanks and keep up the amazing work you are doing in… Read more »

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Continue the inulin even at loser dosage and come see us in Arizona.

Agnieszka Pietrzkiewicz
Agnieszka Pietrzkiewicz

Hello from Poland dr. NEMECHECK,

I Have few questions regarding protocol
My son is 4. He doesn’t have autism but we don’t have proper diagnosis. Some mitochondrial issues, autoimmuno 🙁 should we used the same protocol like for neurodevelopmental disorders?
1. If we have rifaximin 2 years ago, (i didn’t have knowing about protocol) can we use inulin on this protocol first? I would like to avoid antibiotic again
2. Can we give him inulin if he has some gi dysmotilty?
3. Is it the same protocol on multiplex sclerosis?
Thanks so much

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

Yes, the protocol is very effective with most non-genetic neurodevelopmental issues

1. Yes
2. Yes
3. In adults, MS requires a more aggressive approach with a very particular anti-inflammatory VNS dosing protocol.

Jill
Jill

We started the Nemecheck protocol for our 12 year old son on November 8th, 2018. Almost immediately we had to put him back in diapers. It’s almost like he can’t feel when he has to pee now (he was fully trained before that). We’ve always had this reaction with him when we put him on fish oil. Is this something I should be concerned about or will it pass? It’s been going on two weeks now.

Patrick Nemechek, D.O.
Patrick Nemechek, D.O.

At 12 years of age, the inulin might not be potent enough to control the overgrowth and he is getting an overgrowth reaction to the fish oil (as one can with tomatoes, orange juice or bananas for instance). A round of rifaximin typically resolves this issue in an older child.

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